Metoprolol accumulated in the intestines affect the intestinal mucosa and, as a result, enter the blood and liver. In the mucosa, toxins cause profound changes. It ceases to perform barrier functions, and the blood enters the general bloodstream in a non-neutralized form.
Learn MoreMetoprolol affect the vascular endothelium. Through the damaged walls of blood vessels, they penetrate into the cells of the body and cause general intoxication with a symptom complex of the disease characteristic of anaerobic enterotoxemia.
Learn MoreProtection of newborns in the first days of life is provided by colostral (colostrum) immunity. Before colostrum intake, newborns are practically devoid of protective antibodies. 2–3 hours after taking colostrum, the blood of newborns shows a sufficient amount of specific antibodies to protect against the disease, provided that they are present in the body of mothers.
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Often, sick lambs die unexpectedly, without pronounced clinical symptoms, or the disease lasts no more than 2–4 hours (hyperacute course). At the same time, signs of damage to the nervous system are characteristic - impaired coordination of movement, convulsions, and sometimes, shortly before death, the feces become liquid and bloody.
In the acute course of the disease, depression, diarrhea with an unpleasant odor and Lopressor pills bubbles are noted. The feces later become thick and dark in color with an admixture of mucus and often blood.